Effects of Approach-Avoidance Training on the Extinction and Return of Fear Responses

ID 169 2 Reuses

Abstract

Background and Objectives Exposure therapy for anxiety involves confronting a patient with fear-evoking stimuli, a procedure based partially on Pavlovian extinction. Exposure and other extinction-based therapies usually lead to (partial) reduction of fear symptoms, but a substantial number of patients experience a return of fear after treatment. Here we tested whether the combination of fear extinction with modification of approach-avoidance tendencies using an Approach-Avoidance Task (AAT) would result in the further reduction of conditioned fear and/or help prevent return of fear after extinction. Methods Two groups of participants underwent a fear acquisition procedure during which pictures of one neutral object were sometimes paired with shock (CS+), whereas pictures of another neutral object were not (CS−). The next day, in a fear extinction procedure, both objects were presented without shock. During the subsequent joystick AAT, one group primarily pulled CS+ pictures towards themselves and pushed CS− pictures away from themselves; reversed contingencies applied for the other group. Results Approach training was effective in modifying conditioned action tendencies, with some evidence for transfer to a different approach/avoidance task. No group differences in subjective fear or physiological arousal were found during subsequent post- training and return-of-fear testing. Limitations No reliable return-of-fear was observed in either group for either subjective or physiological fear measures. Conclusions Our results suggest that approach training may be of limited value for enhancing the short- and long-term effects of extinction-based interventions.

Authors

Angelos-Miltiadis Krypotos, Department of Clinical Psychology, University of Amsterdam, Amsterdam, Netherlands; Amsterdam Brain and Cognition Center, Amsterdam, Netherlands Inna Arnaudova, Department of Clinical Psychology, University of Amsterdam, Amsterdam, Netherlands; Amsterdam Brain and Cognition Center, Amsterdam, Netherlands Marieke Effting, Department of Clinical Psychology, University of Amsterdam, Amsterdam, Netherlands; Amsterdam Brain and Cognition Center, Amsterdam, Netherlands Merel Kindt, Department of Clinical Psychology, University of Amsterdam, Amsterdam, Netherlands; Amsterdam Brain and Cognition Center, Amsterdam, Netherlands Tom Beckers, Department of Clinical Psychology, University of Amsterdam, Amsterdam, Netherlands; Amsterdam Brain and Cognition Center, Amsterdam, Netherlands; Department of Psychology, KU Leuven, Leuven, Belgium

Year

2015

DOI of Publication

https://doi.org/10.1371/journal.pone.0131581

Is Version of

10.17605/OSF.IO/3APXV

Where was the data collected?

University of Amsterdam, Netherlands

How to Cite

Krypotos, A., & Beckers, T. (2026, April 2). Effects of approach-avoidance training on the extinction and return of fear responses. https://doi.org/10.17605/OSF.IO/3APXV

Participant Information

Participant Age

Participant Sex

Experimental Group

Avoid CS+ Group (n=18): This group was trained during the joystick Approach-Avoidance Task (AAT) to primarily PUSH the joystick (avoid) in response to CS+ pictures (89% of the time) and PULL the joystick (approach) in response to CS− pictures (11% of the time). Approach CS+ Group (n=22): This group was trained during the joystick Approach-Avoidance Task (AAT) to primarily PULL the joystick (approach) in response to CS+ pictures (89% of the time) and PUSH the joystick (avoid) in response to CS− pictures (11% of the time; opposite contingencies).

Stimuli

Drug Administration

No

Conditioning Protocol

Differential

Instructions CS-US Contingencies

Partially instructed (whole exp)

Number of Different US

1

US Modality

electrotactile

US Duration (ms)

2

Time Between CS and US Onset (ms)

7500

Number of Different CS+

1

CS+ Duration (ms)

CS+ 1: Reinforcement Rate (%)

100

CS+ 2: Reinforcement Rate (%)

CS+ 3: Reinforcement Rate (%)

Number of Different CS-

1

CS- Duration (ms)

CS Modality

visual

Data Collected During MRI

No

Measures

skin conductance response

Amplitude of skin conductance response to stimulus.

fear potentiated startle (emg)

trialwise & untransformed

Fear potentiated startle response (electromyography).

US expectancy rating

US expectancy rating of the CS stimuli.

US intensity rating

Intensity rating of the US stimulus.

State Trait Anxiety Inventory (STAI-S)

State Trait Anxiety Inventory (STAI-T)

Anxiety Sensitivity Index (ASI)